SUPT16H antibody (AA 1-329)
Quick Overview for SUPT16H antibody (AA 1-329) (ABIN306912)
Target
See all SUPT16H AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-329
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Purpose
- Rabbit anti Human SPT16 NT
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Cross-Reactivity
- Human, Mouse
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Characteristics
- SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.
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Purification
- Ammonium Sulfate Precipitation
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Immunogen
- Recombinant protein consisting of amino acids 1-329 of the human SPT16 protein conjugated to KLH.
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Isotype
- IgG
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Application Notes
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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Alternative Name
- SPT16
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UniProt
- Q08945
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Pathways
- Chromatin Binding
Target
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