RGR antibody (Intracellular)

Catalog No. ABIN306933

This anti-RGR antibody is a Mouse Monoclonal antibody detecting RGR in IHC and WB. Suitable for Rat.

Quick Overview for RGR antibody (Intracellular) (ABIN306933)

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This RGR antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: 5G10

Product Details anti-RGR Antibody

Binding Specificity: Intracellular

Cross-Reactivity: Mouse, Rat

Characteristics: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Purification: Protein A/G Chromatography

Immunogen: Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha 2b adrenergic receptor.

Isotype: IgG1

Application Details

Application Notes: Antibody detects alpha2B Adrenergic Receptors in Western blots (1-5 μg/mL) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Alternative Name: Adrenergic Receptor

UniProt: P19328