Ceramide Kinase (rProtein-Full Length) antibody
Reactivity: Human
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target
- Ceramide Kinase (rProtein-Full Length)
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- ELISA, Western Blotting (WB)
- Cross-Reactivity
- Human
- Characteristics
- Acylsphingosine kinase, hCERK, Lipid kinase 4, LK4,Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondria-mediated apoptosis. Sphingosine inhibits several protein kinases, including protein kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.
- Immunogen
- Rabbits were immunized with recombinant full-length human ceramide kinase protein
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- Application Notes
- Antibody can be used for Western blotting (1-10 μg/mL). Can also be used for ELISA. Optimal concentration should be evaluated by serial dilutions.
- Restrictions
- For Research Use only
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- Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Target
- Ceramide Kinase (rProtein-Full Length)
- UniProt
- Q8TCT0
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