RPS6KA1 antibody (pSer380)

Catalog No. ABIN307523

The Rabbit Polyclonal anti-RPS6KA1 antibody has been validated for WB, ELISA and IP. It is suitable to detect RPS6KA1 in samples from Human, Mouse, Rat and Hamster.

Quick Overview for RPS6KA1 antibody (pSer380) (ABIN307523)

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-RPS6KA1 Antibody

Binding Specificity: pSer380

Specificity: Detects endogenous levels of human p90RSK only when phosphorylated at Ser380. Does not recognize p90RSK phosphorylated at other sites. It shows some cross-reactivity with RSK2 and RSK3 when phosphorylated at the homologous serine residues. Species cross-reactivity: Hamster, mouse, monkey and rat.

Purification: Protein A purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser380 of human p90RSK (KLH).

Type of Immunogen: Synthetic phospho-peptide

Application Details

Application Notes: Approved: ELISA, IP (1:200), WB (1:1000)

Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:200.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Target Details for RPS6KA1

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Alternative Name: RPS6KA1 / RSK1

Background: Name/Gene ID: RPS6KA1
Subfamily: RSK
Family: Protein Kinase

Synonyms: RPS6KA1, MAPKAPK-1a, p90RSK, p90-RSK 1, Pp90RSK1, Ribosomal S6 kinase 1, RSK-1, S6K-alpha 1, MAPKAP kinase 1a, MAPKAPK1A, p90 s6 kinase, p90S6K, RSK, RSK1, HU-1, p90RSK1, S6K-alpha-1

Gene ID: 6195

UniProt: Q15418

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades