RPS6KA1 antibody (pThr573)

Catalog No. ABIN307525

This Rabbit Polyclonal antibody specifically detects RPS6KA1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Chicken, Hamster and Xenopus laevis.

Quick Overview for RPS6KA1 antibody (pThr573) (ABIN307525)

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reactivity: Human, Mouse, Rat, Chicken, Hamster, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPS6KA1 Antibody

Binding Specificity: pThr573

Specificity: Detects endogenous human p90RSK protein only when phosphorylated at Thr573. Species cross-reactivity: Hamster, mouse and rat. Predicted to cross-react with chicken and Xenopus based on sequence homology.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Thr573 of human p90RSK (90kD) (KLH coupled).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for RPS6KA1

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Alternative Name: RPS6KA1 / RSK1

Background: Name/Gene ID: RPS6KA1
Subfamily: RSK
Family: Protein Kinase

Synonyms: RPS6KA1, MAPKAPK-1a, p90RSK, p90-RSK 1, Pp90RSK1, Ribosomal S6 kinase 1, RSK-1, S6K-alpha 1, MAPKAP kinase 1a, MAPKAPK1A, p90 s6 kinase, p90S6K, RSK, RSK1, HU-1, p90RSK1, S6K-alpha-1

Gene ID: 6195

UniProt: Q15418

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades