CD80 antibody (PE)

Catalog No. ABIN307693

The Rat Monoclonal anti-CD80 antibody has been validated for FACS. It is suitable to detect CD80 in samples from Mouse.

Quick Overview for CD80 antibody (PE) (ABIN307693)

Target: CD80

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD80 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: RMMP-1

Product Details anti-CD80 Antibody (PE)

Specificity: Reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours. Applications include: flow cytometry.

Purification: Purified

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1 μg/10 x10⁶)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.9 % sodium azide, 1 % EIA grade BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light. Store undiluted.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light. Store undiluted.

Target Details for CD80

Target: CD80

Alternative Name: CD80 / B7

Background: Name/Gene ID: CD80

Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1

Gene ID: 941

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints