C7 antibody

Catalog No. ABIN317053

Product Details anti-C7 Antibody

Target: C7 (Complement Component C7 (C7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: This antibody recognises complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. Note that this antibody does not recognise membrane bound complement membrane attack complex. This antibody inhibits lysis of sensitised sheep erythrocytes.

Characteristics: Synonyms: Complement component C7, Complement 7

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Purified human C7

Clone: 030-113-7-5-4

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot. Functional Assays: Removal of Sodium Azide is recommended prior to use.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Expiry Date: 12 months

Target Details for C7

Target: C7 (Complement Component C7 (C7))

Alternative Name: Complement C7 (C7 Products)

Synonyms: A530026G17 antibody, Gm1238 antibody, MGC82368 antibody, c7 antibody, cb349 antibody, wu:fa01f03 antibody, C7 antibody, complement C7 antibody, complement component 7 antibody, complement component 7 S homeolog antibody, complement component 7b antibody, C7 antibody, c7.S antibody, c7b antibody

Background: The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides.Synonyms: Complement 7, Complement component C7

Gene ID: 730

UniProt: P10643

Pathways: Complement System