DAZL antibody (C-Term)

Catalog No. ABIN317430

The Mouse Monoclonal anti-DAZL antibody (Clone 3-11A) (ABIN317430) specifically detects DAZL in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DAZL antibody (C-Term) (ABIN317430)

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DAZL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3-11A

Product Details anti-DAZL Antibody

Binding Specificity: C-Term

Specificity: This antibody is specific for DAZL, a member of the DAZ (deleted in azoospermia) family of RNA binding proteins.

Characteristics: Synonyms: DAZL, DAZH, DAZL1, DAZLA, SPGYLA, Deleted in azoospermia-like, DAZ-like autosomal,Deleted in azoospermia-like 1, DAZ homolog, SPGY-like-autosomal

Purification: Tissue Culture Supernatant.

Immunogen: Synthetic peptide corresponding to sequence within the C terminal domain of human DAZLAA Sequence: CRVHHFRRSRAMLKSV

Isotype: IgG1

Application Details

Application Notes: Western blot. Immunohistochemistry on Paraffin Sections: Does not require protein digestionpre-treatment of paraffin sections e. g. trypsin or pronase prior to staining. Requiresantigen retrieval using heat treatment prior to staining, Sodium Citrate buffer pH 6.0 isrecommended for this purpose. Recommended Positive Control: Ovary or testis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Should this product contain a precipitate we recommend microcentrifugation before use. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for DAZL

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Alternative Name: DAZL

Background: DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is localised to the cytoplasm. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males.Synonyms: DAZ homolog, DAZ-like autosomal, DAZH, DAZL, DAZL1, DAZLA, Deleted in azoospermia-like, Deleted in azoospermia-like 1, SPGY-like-autosomal, SPGYLA

Gene ID: 1618

UniProt: Q92904