EPH Receptor A2 antibody (AA 559-976)

Catalog No. ABIN317512

The Mouse Monoclonal anti-EPH Receptor A2 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect EPH Receptor A2 in samples from Human and Mouse.

Quick Overview for EPH Receptor A2 antibody (AA 559-976) (ABIN317512)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3D7

Product Details anti-EPH Receptor A2 Antibody

Binding Specificity: AA 559-976

Specificity: The antibody recognizes Human and Mouse EPHA2. Other species not tested.

Characteristics: Synonyms: Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2, Tyrosine-protein kinasereceptor ECK

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human EphA2 (559-976 aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 500 - 2,000). Immunohistochemistry (1: 100 - 1: 200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2 / ECK

Background: The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTK). Eph RTKs and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK

Gene ID: 1969

UniProt: P29317

Pathways: RTK Signaling