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TACR1 antibody

TACR1 Reactivity: Human, Rat, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN317654
  • Target See all TACR1 Antibodies
    TACR1 (Tachykinin Receptor 1 (TACR1))
    Reactivity
    • 83
    • 46
    • 23
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 77
    • 6
    • 1
    Rabbit
    Clonality
    • 75
    • 9
    Polyclonal
    Conjugate
    • 45
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TACR1 antibody is un-conjugated
    Application
    • 53
    • 27
    • 19
    • 13
    • 13
    • 12
    • 12
    • 9
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    This antibody detects endogenous levels of NK-1R protein.(region surrounding Lys245)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse and Rat.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product TACR1 Primary Antibody
  • Application Notes
    ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TACR1 (Tachykinin Receptor 1 (TACR1))
    Abstract
    TACR1 Products
    Synonyms
    NK1R antibody, NKIR antibody, SPR antibody, TAC1R antibody, Nk1r antibody, Spr antibody, Tac1r antibody, nk1R antibody, Tacr1 antibody, ASPR antibody, tachykinin receptor 1 antibody, TACR1 antibody, Tacr1 antibody
    Background
    The Neurokinin-1 (NK1) Receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R
    Molecular Weight
    approx. 50 kDa
    Gene ID
    6869
    NCBI Accession
    NP_001049
    UniProt
    P25103
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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