TACR1 antibody
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- Target See all TACR1 Antibodies
- TACR1 (Tachykinin Receptor 1 (TACR1))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TACR1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificity
- This antibody detects endogenous levels of NK-1R protein.(region surrounding Lys245)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse and Rat.
- Purification
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product TACR1 Primary Antibody
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- Application Notes
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- TACR1 (Tachykinin Receptor 1 (TACR1))
- Abstract
- TACR1 Products
- Synonyms
- NK1R antibody, NKIR antibody, SPR antibody, TAC1R antibody, Nk1r antibody, Spr antibody, Tac1r antibody, nk1R antibody, Tacr1 antibody, ASPR antibody, tachykinin receptor 1 antibody, TACR1 antibody, Tacr1 antibody
- Background
- The Neurokinin-1 (NK1) Receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R
- Molecular Weight
- approx. 50 kDa
- Gene ID
- 6869
- NCBI Accession
- NP_001049
- UniProt
- P25103
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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