TACR1 antibody

Catalog No. ABIN317654

The Rabbit Polyclonal anti-TACR1 antibody is suitable to detect TACR1 in samples from Human, Rat and Mouse. It has been validated for WB and IF.

Quick Overview for TACR1 antibody (ABIN317654)

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TACR1 Antibody

Specificity: This antibody detects endogenous levels of NK-1R protein.(region surrounding Lys245)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse and Rat.

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Background: The Neurokinin-1 (NK1) Receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R

Molecular Weight: approx. 50 kDa

Gene ID: 6869

NCBI Accession: NP_001049

UniProt: P25103

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration