MAPK6 antibody

Catalog No. ABIN317675

The Rabbit Polyclonal anti-MAPK6 antibody is suitable to detect MAPK6 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for MAPK6 antibody (ABIN317675)

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAPK6 Antibody

Specificity: This antibody detects endogenous levels of ERK3 protein.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Alternative Name: MAPK6 / ERK3

Background: ERKs (extracellular signal-regulated protein kinases) are members of the Mitogen Activated Protein Kinase (MAPK) family, which play pivotal roles in mediating signal transduction from the cell surface to the nucleus. ERKs are regulated predominantly by extracellular ligands which act through membrane transmembrane receptors with intrinsic or associated tyrosine kinase activity. Unlike the MAP kinases ERK3 is localized in the nucleus in quiescent and growth factor-stimulated cells.Synonyms: Extracellular signal-regulated kinase 3, MAP kinase isoform p97, Mitogen-activated protein kinase 6, Serine/threonine-protein kinase, p97-MAPK

Molecular Weight: approx. 85 kDa

Gene ID: 5597

NCBI Accession: NP_002739

UniProt: Q16659

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C