KAT2A antibody

Catalog No. ABIN317677

This Rabbit Polyclonal antibody specifically detects KAT2A in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for KAT2A antibody (ABIN317677)

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KAT2A Antibody

Specificity: This antibody detects endogenous levels of GCN5 protein.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A / GCN5L2

Background: KAT2A / GCN5 is a transcriptional co-activator that has histone acetyltransferase activity. It exhibits significant histone acetyltransferase activity with core histones but not with nucleosome core particles. KAT2A is a component of the TFTC-HAT and STAGA complexes. KAT2A is also recruited by the viral protein Tat during HIV infection, inducing chromatin remodelling of proviral genes.Synonyms: General control of amino acid synthesis protein 5-like 2, HGCN5, Histone acetyltransferase GCN5, Histone acetyltransferase KAT2A, HsGCN5, Lysine acetyltransferase 2A, STAF97

Molecular Weight: approx. 100 kDa

Gene ID: 2648

NCBI Accession: NP_066564

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation