FZD3 antibody

Catalog No. ABIN317750

Product Details anti-FZD3 Antibody

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: Frizzled-3 antibody detects endogenous levels of Frizzled-3 protein.(region surrounding Arg524)

Purification: Affinity-chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FZD3

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Alternative Name: FZD3 / Frizzled-3 (FZD3 Products)

Background: FZD3 (Frizzled 3) belongs to the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD3 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.Synonyms: Fz-3, hFz3

Molecular Weight: approx. 76 kDa

Gene ID: 7976

NCBI Accession: NP_059108

UniProt: Q9NPG1

Pathways: WNT Signaling, Tube Formation