FZD3 antibody
Quick Overview for FZD3 antibody (ABIN317750)
Target
See all FZD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Frizzled-3 antibody detects endogenous levels of Frizzled-3 protein.(region surrounding Arg524)
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Purification
- Affinity-chromatography
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Application Notes
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FZD3 (Frizzled Family Receptor 3 (FZD3))
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Alternative Name
- FZD3 / Frizzled-3
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Background
- FZD3 (Frizzled 3) belongs to the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD3 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.Synonyms: Fz-3, hFz3
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Molecular Weight
- approx. 76 kDa
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Gene ID
- 7976
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NCBI Accession
- NP_059108
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UniProt
- Q9NPG1
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Pathways
- WNT Signaling, Tube Formation
Target
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