MC5 Receptor antibody

Catalog No. ABIN317755

Product Details anti-MC5 Receptor Antibody

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC5 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: MC5-R antibody detects endogenous levels of MC5-R protein. (region surrounding Glu308)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MC5 Receptor

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Alternative Name: MC5-R (MC5R Products)

Synonyms: MC2 antibody, MC5R antibody, MC5 antibody, mc5br antibody, mc5ra antibody, zMC5b antibody, zgc:194217 antibody, mc5ar antibody, mc5rb antibody, zMC5a antibody, melanocortin 5 receptor antibody, melanocortin 5b receptor antibody, melanocortin 5a receptor antibody, MC5R antibody, Mc5r antibody, mc5r antibody, mc5rb antibody, mc5ra antibody

Background: The melanocortin family comprises the α-, β- and γ-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane, G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC-2, MC5R, Melanocortin receptor 5

Molecular Weight: approx. 40 kDa

Gene ID: 4161

NCBI Accession: NP_005904

UniProt: P33032

Pathways: cAMP Metabolic Process