OPN4 antibody

Catalog No. ABIN317763

The Rabbit Polyclonal anti-OPN4 antibody (ABIN317763) specifically detects OPN4 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for OPN4 antibody (ABIN317763)

Target: OPN4 (Opsin 4 (OPN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPN4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-OPN4 Antibody

Specificity: This antibody detects endogenous levels of Melanopsin protein.(region surrounding Leu470)

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1/1000approx. 1/5000. Western Blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for OPN4

Target: OPN4 (Opsin 4 (OPN4))

Alternative Name: Melanopsin

Background: Melanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that parallels that of the classic rod and cone system. This second system reports directly to the suprachiasmatic nucleus and is responsible for regulation of circadian rhythms. Melanopsin is believed to be the primary photopigment responsible for the regulation of these circadian rhythms, and Melanopsin knockout mice have been generated which demonstrate decreased capacity to entrain to light and dark cycles.Synonyms: MOP, OPN4, Opsin-4

Molecular Weight: approx. 55 kDa

Gene ID: 94233

NCBI Accession: NP_001025186

UniProt: Q9UHM6