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OPN4 antibody (AA 400-480)

OPN4 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7215736
  • Target See all OPN4 Antibodies
    OPN4 (Opsin 4 (OPN4))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 400-480
    Reactivity
    • 7
    • 1
    • 1
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 7
    This OPN4 antibody is un-conjugated
    Application
    • 7
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purpose
    Melanopsin Polyclonal Antibody
    Specificity
    Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Immunogen
    Synthesized peptide derived from the C-terminal region of human Melanopsin at AA range: 400-480
    Isotype
    IgG
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
    Comment

    Primary Antibody

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target
    OPN4 (Opsin 4 (OPN4))
    Alternative Name
    Melanopsin (OPN4 Products)
    Synonyms
    MOP antibody, 1110007J02Rik antibody, Gm533 antibody, OPN4-2 antibody, cOpn4L antibody, melanopsin antibody, opn4-A antibody, Xmop antibody, opn4 antibody, opn4d antibody, opsin 4 antibody, opsin 4 (melanopsin) antibody, melanopsin antibody, melanopsin-B-like L homeolog antibody, opsin 4a (melanopsin) antibody, OPN4 antibody, Opn4 antibody, LOC100303707 antibody, LOC100485437.L antibody, opn4a antibody
    Background
    Rabbit Anti-Melanopsin Polyclonal Antibody,OPN4, MOP, Melanopsin, Opsin-4,Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,Melanopsin
    Molecular Weight
    observerd band 55kDa
    Gene ID
    94233
    UniProt
    Q9UHM6
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