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FUBP3 antibody

FUBP3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN317906
  • Target See all FUBP3 Antibodies
    FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))
    Reactivity
    • 35
    • 9
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 29
    • 6
    Rabbit
    Clonality
    • 31
    • 4
    Polyclonal
    Conjugate
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    This FUBP3 antibody is un-conjugated
    Application
    • 35
    • 18
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of FBP3 protein.(region surrounding Arg241)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product FUBP3 Primary Antibody
  • Application Notes
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))
    Alternative Name
    FUBP3 (FUBP3 Products)
    Synonyms
    FBP3 antibody, Marta2 antibody, A330051M14Rik antibody, AV006371 antibody, zgc:101598 antibody, far upstream element binding protein 3 antibody, far upstream element-binding protein 3 antibody, far upstream element binding protein 3 S homeolog antibody, far upstream element (FUSE) binding protein 3 antibody, FUBP3 antibody, LOC100196681 antibody, Fubp3 antibody, fubp3.S antibody, fubp3 antibody
    Background
    Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxylterminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.Synonyms: FBP3, FUSE-binding protein 3, Far upstream element-binding protein 3
    Molecular Weight
    approx. 60 kDa
    Gene ID
    8939
    NCBI Accession
    NP_003925
    UniProt
    Q96I24
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