GAB2 antibody (pTyr452)

Catalog No. ABIN3182363

This Rabbit Polyclonal antibody specifically detects GAB2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GAB2 antibody (pTyr452) (ABIN3182363)

Target: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GAB2 Antibody

Binding Specificity: pTyr452

Specificity: Phospho-Gab 2 (Y452) Polyclonal Antibody detects endogenous levels of Gab 2 protein only when phosphorylated at Y452.

Characteristics: Rabbit Polyclonal to Phospho-Gab 2 (Y452).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Gab 2 around the phosphorylation site of Y452.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:40000,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for GAB2

Target: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Alternative Name: Gab 2

Molecular Weight: 75 kDa

Gene ID: 9846

UniProt: Q9UQC2

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect