Glucagon antibody (N-Term)

Catalog No. ABIN318563

Product Details anti-Glucagon Antibody

Target: Glucagon (GCG)

Binding Specificity: AA 1-12, N-Term

Reactivity: Human, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody recognises the pancreatic polypeptide hormone Glucagon, whose actions are antagonistic to insulin. Tumours arising from glucagon producing cells are termed glucagonomas, and this antibody may be useful in identifying such tumours.

Purification: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Porcine glucagon, amino acids 1-12, conjugated with bTG.

Isotype: IgG

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: Glucagon (GCG Products)

Synonyms: GLP1 antibody, GLP2 antibody, GRPP antibody, GLP-1 antibody, Glu antibody, PPG antibody, GCG antibody, gcg-A antibody, gcg1 antibody, glucagon antibody, glucagon L homeolog antibody, GCG antibody, Gcg antibody, gcg.L antibody

Background: Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.Synonyms: GCG

Gene ID: 2641

NCBI Accession: NP_002045

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling