LHB antibody

Catalog No. ABIN318598

This Rabbit Polyclonal antibody specifically detects LHB in WB and IHC (fro). It exhibits reactivity toward Pig.

Quick Overview for LHB antibody (ABIN318598)

Target: LHB (Luteinizing Hormone beta Polypeptide (LHB))

Reactivity: Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LHB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LHB Antibody

Specificity: This antibody is specific for porcine luteinizing hormone and does not react with GH, TSH, LH alpha or prolactin. Minimal reactivity has been observed with FSH.

Purification: Ammonium sulphate precipitation

Immunogen: Porcine luteinizing hormone

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on frozen sections: 1/200 - 1/500. Western Blot: 1/300 - 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Reconstitute with 50 μL sterile distilled water. For long term storage the addition of a preservative is recommended.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to and following reconstitution store the antibody at -20 °C.

Target Details for LHB

Target: LHB (Luteinizing Hormone beta Polypeptide (LHB))

Alternative Name: Luteinizing Hormone beta (LSH-Beta)

Target Type: Hormone

Background: Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

Gene ID: 3972

NCBI Accession: NP_000885

UniProt: P01229

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process