IRF7 antibody (Middle Region)
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- Target See all IRF7 Antibodies
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects Human Interferon Regulatory Factor 7 (IRF7). Other species not tested.
- Purification
- Affinity Chromatography
- Immunogen
- 14 amino acid peptide sequence near the center of Human IRF7.
- Isotype
- IgG
- Top Product
- Discover our top product IRF7 Primary Antibody
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- Application Notes
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Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 51 kDa in 293 whole celllysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.02 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
- Alternative Name
- IRF7 (IRF7 Products)
- Background
- IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7
- Gene ID
- 3665
- NCBI Accession
- NP_001563
- UniProt
- Q92985
- Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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