CX3CR1 antibody (N-Term)

Catalog No. ABIN318971

The Rabbit Polyclonal anti-CX3CR1 antibody is suitable to detect CX3CR1 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for CX3CR1 antibody (N-Term) (ABIN318971)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CX3CR1 Antibody

Binding Specificity: AA 2-21, N-Term

Specificity: This antibody recognizes an epiptope within the N-terminal region (NT) of Human CX3CR1, a 40.4 kDa seven trans-membrane protein.

Purification: Affinity Chromatography

Immunogen: A peptide corresponding to amino acids 2-21 of Human CX3CR1.

Isotype: IgG

Application Details

Application Notes: Western Blot: 0.5-1.0 μg/mL. Detects a band of approximately 50 kDa in human spleen celllysates. Immunohistochemistry on Paraffin Sections: 2.0 μg/mL. Positive Control: Human Heart Tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1 / GPR13

Background: CX3CR1, known also as fractalkine receptor, is the receptor for CX3CL1 and acts as a co-receptor with CD4 for the HIV-1 envelope protein. It is expressed in a variety of human tissues and mediates leucocyte adhesion and migration.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

Gene ID: 1524

NCBI Accession: NP_001328

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin