TYK2 antibody (pTyr1054)

Catalog No. ABIN319229

The Rabbit Polyclonal anti-TYK2 antibody is suitable to detect TYK2 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for TYK2 antibody (pTyr1054) (ABIN319229)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TYK2 Antibody

Binding Specificity: pTyr1054

Specificity: This antibody detects endogenous levels of TYK2 only when phosphorylated at Tyrosine 1054.

Purification: Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R).

Application Details

Application Notes: Western blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at-20 °C.

Target Details for TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Alternative Name: TYK2

Background: Synonyms: JTK1, Non-receptor tyrosine-protein kinase TYK2

Gene ID: 7297

NCBI Accession: NP_003322

UniProt: P29597

Pathways: JAK-STAT Signaling, Hepatitis C