Integrin beta 3 antibody (Tyr785)

Catalog No. ABIN319337

The Rabbit Polyclonal anti-Integrin beta 3 antibody has been validated for WB. It is suitable to detect Integrin beta 3 in samples from Human and Mouse.

Quick Overview for Integrin beta 3 antibody (Tyr785) (ABIN319337)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin beta 3 Antibody

Binding Specificity: Tyr785

Purification: Immunoaffinity Chromatography.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Integrin beta 3 around the phosphorylation site of Tyrosine 785 (I-T-YP-R-G).

Application Details

Application Notes: Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at-20 °C.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: CD61 / ITGB3

Background: Human Integrin beta 3 (CD61) antigen is a 90-110 kDa glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The platelet glycoprotein is the integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa

Gene ID: 9606

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex