CXCR7 antibody (APC)

Catalog No. ABIN332284

This Mouse Monoclonal antibody specifically detects CXCR7 in FACS, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CXCR7 antibody (APC) (ABIN332284)

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR7 antibody is conjugated to APC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CXCR7 Antibody (APC)

Specificity: Recognizes the five distinct human CXCR7 transfectants, but not their respective parental lines. It also reacts with MCF-7 cells expression of CXCR7. This antibody does not react with monocytes or lymphocytes by flow cytometry. An underestimation of CXCR7 expression on certain cell types has been reported.

Purification: Protein G purified

Immunogen: Human CXCR7 encoding plasmid.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (50 μg/mL), IHC, IHC-P

Usage: Suitable for use in Flow Cytometry and Immunohistochemistry. Flow Cytometry: 50 μg/mL 10 μL labels 1-2.5x10^5 cells in a total reaction volume not exceeding 200 μL. Immunohistochemistry (paraffin sections): 8-25 μg/mL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose.

Handling Advice: avoid freeze thaw cycles.

Storage: -20 °C

Storage Comment: Lyophilized and resuspended forms: store at -20°C.

Target Details for CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Alternative Name: ACKR3 / CXCR7

Background: Name/Gene ID: ACKR3
Subfamily: Chemokine
Family: GPCR

Synonyms: ACKR3, Chemokine orphan receptor 1, CMKOR1, CXCR7, CXC-R7, GPRN1, RDC1, RDC-1, CXCR-7, G-protein coupled receptor 159, GPR159

Gene ID: 57007

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling