CTLA4 antibody (Biotin)

Catalog No. ABIN334158

This anti-CTLA4 antibody is a Mouse Monoclonal antibody detecting CTLA4 in FACS, IHC and IHC (fro). Suitable for Human.

Quick Overview for CTLA4 antibody (Biotin) (ABIN334158)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTLA4 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ANC152-2-8H5

Product Details anti-CTLA4 Antibody (Biotin)

Specificity: Recognizes human CTLA-4 expressed on activated T cells. Blocks binding of Cd152 (CTLA-4) Ig fusion protein to it CD80/CD86 receptor.

Purification: Protein A purified

Immunogen: Stimulated human PBLs and human CD152 Ig fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr

Usage: Suitable for use in Flow Cytometry, ELISA, Immunohistochemistry. Immunohistochemistry: Frozen sections. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % glycerol, 0.2 % BSA, 0.04 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CTLA4 / CD152

Background: Name/Gene ID: CTLA4

Synonyms: CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform

Gene ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints