ASY1 antibody
Quick Overview for ASY1 antibody (ABIN334570)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- Anti-ASY1 | Asynaptic phenotype protein 1 (monoclonal)
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Cross-Reactivity (Details)
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Triticum aestivum
Not reactive in: No confirmed exceptions from predicted reactivity are currently known -
Predicted Reactivity
- Triticum aestivum
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Purification
- Protein G purified
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Immunogen
- KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 UniProt: A7TVU8
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Application Notes
- 1: 10 000 (ELISA), 1: 1000 (WB)
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- For reconstitution add 50 μL of sterile water/tube
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Buffer
- Total IgG. Protein G purified purified from Cell culture supernatant.
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Handling Advice
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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Storage
- -20 °C
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Storage Comment
- Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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- ASY1 (DNA-Binding HORMA Protein (ASY1))
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Alternative Name
- ASY1
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Background
- Pairing and synapsis of homologous chromosomes is required for normal chromosome segregation and the exchange of genetic material via recombination during meiosis. Synapsis is complete at pachytene following the formation of a tri-partite proteinaceous structure known as the synaptonemal complex (SC). In yeast, HOP1 is essential for formation of the SC, and localises along chromosome axes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica (BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutants that display decreased fertility due to severely reduced synapsis of homologous chromosomes. Analysis of these genes has indicated that they play a similar role to HOP1 in pairing and formation of the SC through localisation to axial/lateral elements of the SC.
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Molecular Weight
- 66.3 kDa
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Gene ID
- 100126246
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UniProt
- A7TVU8
Target
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