Malondialdehyde antibody

Catalog No. ABIN335417

Product Details anti-Malondialdehyde Antibody

Target: Malondialdehyde (MDA)

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: This Malondialdehyde antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: Specific for MDA modified protein (especially DHP-lysine) in all species.

Purification: Protein A purified

Immunogen: MDA-modified Keyhole-Limpet Hemocyanin.

Clone: 1F83

Isotype: IgG2a lambda

Application Details

Application Notes: IHC: Suggested concentration is 0.5-1.0 ug/mL on paraformaldehyde fixed tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid:100 ug IgG/mL in 10 mM PBS containing 0.1 % NaN 3 and 0.1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Malondialdehyde antibody (ABIN335417)

Yamada, Kumazawa, Ishii, Nakayama, Itakura, Shibata, Kobayashi, Sakai, Osawa, Uchida: "Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine." in: Journal of lipid research, Vol. 42, Issue 8, pp. 1187-96, (2001) (PubMed).

Target Details for Malondialdehyde

Target: Malondialdehyde (MDA)

Alternative Name: Malondialdehyde / MDA (MDA Products)

Target Type: Chemical

Background: Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative. This monoclonal antibody is specific for the MDA-modified protein, especially DHP-lysine type derivative.