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FLIP antibody (N-Term)

CFLAR Reactivity: Human, Mouse, Rat WB, EIA Host: Mouse Monoclonal 5D8 unconjugated
Catalog No. ABIN336100
  • Target See all FLIP (CFLAR) Antibodies
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Binding Specificity
    • 16
    • 15
    • 15
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-376, N-Term
    Reactivity
    • 95
    • 66
    • 56
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 86
    • 14
    • 2
    Mouse
    Clonality
    • 88
    • 14
    Monoclonal
    Conjugate
    • 54
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This FLIP antibody is un-conjugated
    Application
    • 97
    • 39
    • 27
    • 26
    • 21
    • 20
    • 14
    • 14
    • 13
    • 10
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    The antibody recognizes FLIP.
    Characteristics
    Synonyms: c-FLIP, CLARP, MRIT, CASH, FLAME-1, CASP8AP1, Usurpin, CASP8 and FADD-like apoptosisregulator, Caspase-eight-related protein, Inhibitor of FLICE, Cellular FLICE-like inhibitoryprotein, Caspase-like apoptosis regulatory protein, MACH-related inducer of toxicity,Caspase homolog, FADD-like antiapoptotic molecule 1
    Purification
    Affinity Chromatography on Protein G
    Immunogen
    Recombinant human FLIP (aa 1-376) purified from E. coli.
    Clone
    5D8
    Isotype
    IgG3
    Top Product
    Discover our top product CFLAR Primary Antibody
  • Application Notes
    ELISA. Western Blot (1/500-1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Alternative Name
    CFLAR / Casper / I-FLICE (CFLAR Products)
    Synonyms
    Clarp1 antibody, cflar antibody, CFLAR antibody, FLIP antibody, CASH antibody, CASP8AP1 antibody, CLARP antibody, Casper antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, I-FLICE antibody, MRIT antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, 2310024N18Rik antibody, A430105C05Rik antibody, Cash antibody, ENSMUSG00000072980 antibody, Flip antibody, Gm9845 antibody, c-Flip antibody, CASP8 and FADD-like apoptosis regulator a antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator S homeolog antibody, CASP8 and FADD-like apoptosis regulator antibody, cflara antibody, CFLAR antibody, cflar antibody, cflar.S antibody, Cflar antibody
    Background
    FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and Caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (Death Receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (Tumor Necrosis Factor Receptor 1).Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
    Gene ID
    8837
    UniProt
    O15519
    Pathways
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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