Calcitonin antibody
Quick Overview for Calcitonin antibody (ABIN336940)
Target
See all Calcitonin (Calca) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- Synthetic peptide from human Calcitonin conjugated to carrier protein
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Application Notes
- Immunohistochemistry (IHC) 1:50-1:200 using polymer or streptavidin biotin system. For 30 minute at room temperature. The optimum dilution should be determined by the individual lab. General Reference: Holm, R, J Pathology, 158: 213-217,1989 Positive Control: Human thyroid or medulary carcinoma. Cellular Localization: Cytoplasmic.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Total immunoglobulin fraction in10 mM PO4, 150 mM NaCl, pH 7.4, 0.05% sodium azide. HostRabbit ReagentConc. antibody
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- Calcitonin (Calca)
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Alternative Name
- Calcitonin
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Background
- Calcitonin is a 32-amino acid polypeptide hormone that is produced in human primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body It acts to reduce blood calcium (Ca 2+ ), opposing the effects of parathyroid hormone (PTH) Calcitonin staining can detect C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors.
Target
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