F2RL2 antibody
Quick Overview for F2RL2 antibody (ABIN337281)
Target
See all F2RL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Brand
- IHC-plus™
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Specificity
- Recognizes human Prothrombin, prethrombin-1, fragment 2, meizothrombin. Inhibits clotting and prothrombin activation.
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Purification
- Ion exchange chromatography
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Immunogen
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Human Prothrombin.
Type of Immunogen: Purified protein -
Isotype
- IgG2a
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Application Notes
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Approved: ELISA (5 - 10 μg/mL), IHC, IHC-P (5 μg/mL), WB (10 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Supplied as a liquid in 50 % glycerol, ddH2O. Sourced from ascites.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))
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Alternative Name
- F2 / Prothrombin / Thrombin
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Background
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Name/Gene ID: F2
Subfamily: Serine S1
Family: Protease
Synonyms: F2, Prothrombin B-chain, Coagulation factor II, FACTOR II, Prothrombin, PT, RPRGL2, Serine protease, THPH1, Thrombin -
Gene ID
- 2147
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UniProt
- P00734
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Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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