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Progesterone Receptor antibody (C-Term)

The Mouse Monoclonal anti-Progesterone Receptor antibody (ABIN342255) specifically detects Progesterone Receptor in WB. The antibody is reactive with Human samples.
Catalog No. ABIN342255
-15% Promotion 2026
$763.58
$898.33
save $134.75 (-15 %)
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 11 to 14 Business Days

Quick Overview for Progesterone Receptor antibody (C-Term) (ABIN342255)

Target

See all Progesterone Receptor (PGR) Antibodies
Progesterone Receptor (PGR)

Reactivity

  • 229
  • 41
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Human

Host

  • 165
  • 69
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Mouse

Clonality

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Monoclonal

Conjugate

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This Progesterone Receptor antibody is un-conjugated

Application

  • 191
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Western Blotting (WB)
  • Binding Specificity

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    C-Term

    Specificity

    Recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.

    Purification

    Protein G purified

    Immunogen

    6-His fusion protein containing the region encoding aa 1-101 of human progesterone receptor expressed in E. coli.

    Type of Immunogen: Fusion protein

    Isotype

    IgG2a
  • Application Notes

    Approved: WB (1 - 5 μg/mL)

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4

    Handling Advice

    Avoid freeze/thaw cycles.

    Storage

    -80 °C

    Storage Comment

    Store at -70°C, avoid freeze/thaw cycles.
  • Target

    Progesterone Receptor (PGR)

    Alternative Name

    PGR/PR/Progesterone Receptor

    Background

    Name/Gene ID: PGR
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: PGR, NR3C3, PR, Progesterone receptor

    Gene ID

    5241

    UniProt

    P06401

    Pathways

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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