Progesterone Receptor antibody (C-Term)

Catalog No. ABIN342255

This anti-Progesterone Receptor antibody is a Mouse Monoclonal antibody detecting Progesterone Receptor in WB. Suitable for Human.

Quick Overview for Progesterone Receptor antibody (C-Term) (ABIN342255)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: C-Term

Specificity: Recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.

Purification: Protein G purified

Immunogen: 6-His fusion protein containing the region encoding aa 1-101 of human progesterone receptor expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Application Details

Application Notes: Approved: WB (1 - 5 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR/Progesterone Receptor

Background: Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: PGR, NR3C3, PR, Progesterone receptor

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration