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MTBP antibody (AA 122-139)

This Rabbit Polyclonal antibody specifically detects MTBP in WB. It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN342358

Quick Overview for MTBP antibody (AA 122-139) (ABIN342358)

Target

See all MTBP Antibodies
MTBP (MDM2 Binding Protein (MTBP))

Reactivity

  • 43
  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 41
  • 2
Rabbit

Clonality

  • 41
  • 2
Polyclonal

Conjugate

  • 19
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MTBP antibody is un-conjugated

Application

  • 32
  • 14
  • 13
  • 13
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-139

    Specificity

    Recognizes human and mouse MTBP which is involved in the p53 network of tumor suppression. p53 transcriptionally activates the MDM2 gene, then the translated MDM2 protein binds to p53 and promotes degradation of p53. MTBP binds to MDM2 and inhibits the modulating effect of MDM2 on p53. MTBP is expressed in a variety of normal tissues.

    Purification

    Immunoaffinity purified

    Immunogen

    Peptide corresponding to aa 122-139 of human MTBP. This sequence differs from that of mouse by three amino acids.

    Type of Immunogen: Synthetic peptide
  • Application Notes

    Approved: WB (0.5 - 1 μg/mL)

    Usage: Western Blot: A band of 104 kD is detected.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.02 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C,-20 °C

    Storage Comment

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target

    MTBP (MDM2 Binding Protein (MTBP))

    Alternative Name

    MTBP

    Background

    Name/Gene ID: MTBP

    Synonyms: MTBP, Mdm2-binding protein, MDM2BP, HMTBP

    Gene ID

    27085

    UniProt

    Q96DY7
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