RFC3 antibody

Catalog No. ABIN342384

Product Details anti-RFC3 Antibody

Target: RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RFC3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recognizes the p37 subunit of human and yeast (S. cerevisiae) Replication Factor C (RFC). RFC is a heteropentameric protein consisting of p140, p40, p38, p37, and p36 subunits, RFC participates in targeting DNA polymerase ~ processivity factor (PCNA) on to a primed DNA template during DNA synthesis and repair. RFC has also been associated with DNA repair in conjunction with a PCNA-like heterotrimer of Hus1, Rad1, and Rad9.

Purification: Protein G purified

Immunogen: Recombinant protein corresponding to the p37 subunit of human Replication Factor C expressed in E. coli.

Type of Immunogen: Recombinant protein

Clone: 1320

Isotype: IgG2b

Application Details

Application Notes: Approved: WB (1:2000)

Usage: Western Blot: A band of 37 kD is detected.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for RFC3

Target: RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Alternative Name: RFC3 (RFC3 Products)

Background: Name/Gene ID: RFC3

Synonyms: RFC3, Activator 1 38 kDa subunit, A1 38 kDa subunit, Activator 1 subunit 3, Replication factor C subunit 3, RF-C 38 kDa subunit, RFC, 38 kD subunit, RFC38

Gene ID: 5983

UniProt: P40938

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA