CD14 antibody
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- Target See all CD14 Antibodies
- CD14
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD14 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Purification
- Protein G purified
- Immunogen
- Affinity purified recombinant human CD14
- Top Product
- Discover our top product CD14 Primary Antibody
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- Application Notes
- Suitable for Immunostaining of CD14 positive cells, Immunoprecipitation, Western blot. no significant but small inhibition of LPS binding to human CD14, Binding titre at human CD14+CHO cells (FACS) more than 1:5.000. Recommended working dilution: 1: 100 till 1.000 Binding at mouse CD14 transfected CHO+ cells more than 1:1000 (recommanded working dilution 1:10 til 1:100)
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 0.1 ml without NaN3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex." in: Infection and immunity, Vol. 68, Issue 12, pp. 6519-25, (2000) (PubMed).
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Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex." in: Infection and immunity, Vol. 68, Issue 12, pp. 6519-25, (2000) (PubMed).
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- Target
- CD14
- Alternative Name
- CD14 (CD14 Products)
- Background
- The antiserum represents a marker for human CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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