CHRNE antibody

Catalog No. ABIN347199

Product Details anti-CHRNE Antibody

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Reacts with human and mouse CHRNE protein

Cross-Reactivity: Rat (Rattus)

Cross-Reactivity (Details): May cross reacts with protein from rat and other species due to sequence homology (> 80 % ).

Purification: Antiserum

Immunogen: Synthetic peptide derived from the human CHRNE protein.

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:200 - 1:1000) WB(1:500 - 1:5000)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for CHRNE

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Alternative Name: Acetylcholine Receptor Protein, epsilon Subunit (CHRNE) (CHRNE Products)

Synonyms: ACHRE antibody, CMS1D antibody, CMS1E antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody, AChrepsilon antibody, Acre antibody, nAChRE antibody, im:7154697 antibody, zgc:101010 antibody, CHRNE antibody, cholinergic receptor nicotinic epsilon subunit antibody, cholinergic receptor, nicotinic, epsilon polypeptide antibody, cholinergic receptor, nicotinic epsilon L homeolog antibody, cholinergic receptor, nicotinic, epsilon antibody, CHRNE antibody, Chrne antibody, chrne.L antibody, chrne antibody

Background: Belongs to the ligand-gated ion channel family. Acetylcholine receptor subfamily. Epsilon/CHRNE sub-subfamily. Defects in CHRNE are a cause of congenital myasthenic syndrome slow-channel type (SCCMS), congenital myasthenic syndrome fast-channel type (FCCMS) and congenital myasthenic syndrome with acetylcholine receptor deficiency (CMS-ACHRD).

Gene ID: 1145

UniProt: Q04844