DPYSL2 antibody (pSer465)

Catalog No. ABIN347275

This Rabbit Polyclonal antibody specifically detects DPYSL2 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for DPYSL2 antibody (pSer465) (ABIN347275)

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPYSL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DPYSL2 Antibody

Binding Specificity: pSer465

Specificity: Reacts with human 65 kDa CRMP-2 with a phosphoserine 465

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross reacts with mouse and rat proteins. Do not react with CRMP-1, CRMP-3, CRMP-4 or CRMP-5.

Purification: Antiserum

Immunogen: A 15 residue synthetic peptide of human CRMP-2 containing pS465

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/200 - WB : 1/200 to 1/500

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Alternative Name: Collapsin Response Mediator Protein 2

Background: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

UniProt: Q16555

Pathways: Regulation of Cell Size