NPPA antibody (C-Term)

Catalog No. ABIN347675

The Rabbit Polyclonal anti-NPPA antibody is suitable to detect NPPA in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for NPPA antibody (C-Term) (ABIN347675)

Target: NPPA (Natriuretic Peptide A (NPPA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NPPA Antibody

Binding Specificity: C-Term

Specificity: Reacts with human 17 kDa ANF protein clived from Natriuretic peptides A

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross react with proteins from mouse, rat and other species due to sequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of human ANF protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/200 - WB: 1/100 to 1/1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for NPPA

Target: NPPA (Natriuretic Peptide A (NPPA))

Alternative Name: Atrial Natriuretic Factor (ANF/NPPA)

Background: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

UniProt: P01160