HS6ST1 antibody

Catalog No. ABIN347741

The Rabbit Polyclonal anti-HS6ST1 antibody is suitable to detect HS6ST1 in samples from Human. It has been validated for ELISA, WB and IHC.

Quick Overview for HS6ST1 antibody (ABIN347741)

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS6ST1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HS6ST1 Antibody

Specificity: Reacts with human 48 kDa HS6ST1 protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Cross reacts with proteins from mouse and many other species due to sequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from an internal domain of HS6ST1

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/200 to 1/1 000 - WB : 1/500 to 1/5 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for HS6ST1

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Alternative Name: Heparan-Sulfate 6-O-Sulfotransferase 1 (HS6ST-1)

Background: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. Expressed in fetal brain.

UniProt: O60243

Pathways: Glycosaminoglycan Metabolic Process