BCL11B antibody (N-Term)

Catalog No. ABIN347801

The Rabbit Polyclonal anti-BCL11B antibody is suitable to detect BCL11B in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for BCL11B antibody (N-Term) (ABIN347801)

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL11B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-BCL11B Antibody

Binding Specificity: N-Term

Specificity: Reacts with human 95 kDa protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Cross reacts with human BCL11A (91 kDa). May cross react with BCL11B & A from mouse and other species, due to the homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Nter domain of common domain of human BCL-11B and BCL-11A

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for BCL11B

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Alternative Name: B-Cell Lymphoma/leukemia 11B (BCL-11B)

Background: Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element

UniProt: Q9C0K0