ATG10 antibody

Catalog No. ABIN7698503

The Sheep Polyclonal anti-ATG10 antibody is suitable to detect ATG10 in samples from Human. It has been validated for WB and IHC.

Quick Overview for ATG10 antibody (ABIN7698503)

Target: ATG10 (Autophagy Related 10 (ATG10))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This ATG10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ATG10 Antibody

Purpose: Sheep antibody to ATG10

Specificity: Specific for ATG10.

Cross-Reactivity: Human

Cross-Reactivity (Details): other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human ATG10 conjugated to an immunogenic carrier protein has been used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for ATG10

Target: ATG10 (Autophagy Related 10 (ATG10))

Alternative Name: ATG10

Background: Autophagocytosis is a starvation-induced process responsible for transport of cytoplasmic proteins to the vacuole. FUNCTION: Plays a role in autophagy. ATG12-conjugating enzyme (E2-like enzyme) likely serves as an ATG5-recognition molecule. SUBUNIT: Interacts with MAP1LC3A. By interacting with MAP1LC3A it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7. SUBCELLULAR LOCATION: Cytoplasm.

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagy