SHANK3 antibody
Quick Overview for SHANK3 antibody (ABIN350832)
Target
See all SHANK3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Rabbit antibody to SHANK3
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Specificity
- Specific for SHANK3.
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Cross-Reactivity
- Human, Mouse, Rat
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Cross-Reactivity (Details)
- Other species not yet tested.
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Purification
- IgG
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Immunogen
- A synthetic peptide from human SHANK3 conjugated to blue carrier protein was used as the antigen.
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Isotype
- IgG
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anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (HRP)
SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (FITC)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Biotin)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (PE)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 PE
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (APC)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 APC
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (PerCP)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 594)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 488)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 390)SHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 Atto 390
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibodySHANK3 Reactivity: Rat WB, IHC, IP, ICC, IF, AA Host: Mouse Monoclonal S69 unconjugated
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Application Notes
- IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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Handling Advice
- Avoid freeze and thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Expiry Date
- 12 months
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- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
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Alternative Name
- SHANK3
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Background
- Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer respectively and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. Subcellular location: Cytoplasm. Cell junction ‰ synapse. Cell junction ‰ synapse ‰ postsynaptic cell membrane ‰ postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD. Tissue specificity: Widely expressed in brain.
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UniProt
- Q9BYB0
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Pathways
- Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
Target
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