Synaptophysin antibody

Catalog No. ABIN350898

This anti-Synaptophysin antibody is a Sheep Polyclonal antibody detecting Synaptophysin in WB and IHC. Suitable for Human.

Quick Overview for Synaptophysin antibody (ABIN350898)

Target: Synaptophysin (SYP)

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Synaptophysin Antibody

Purpose: Sheep antibody to Synaptophysin

Specificity: Specific for Synaptophysin.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG. Filter-sterilised UV-C irradiated pH 3.5 acidified then neutralised.

Immunogen: A synthetic peptide from human Synaptophysin (SYP) conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: Synaptophysin

Background: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. FUNCTION: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. SUBUNIT: Homohexamer or homotetramer. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane, Multi-pass membrane protein.

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity