Synaptophysin antibody (Internal Region)

Catalog No. ABIN350900

The Sheep Polyclonal anti-Synaptophysin antibody has been validated for WB and IHC. It is suitable to detect Synaptophysin in samples from Mouse.

Quick Overview for Synaptophysin antibody (Internal Region) (ABIN350900)

Target: Synaptophysin (SYP)

Reactivity: Mouse

Host: Sheep

Clonality: Polyclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Synaptophysin Antibody

Binding Specificity: Internal Region

Purpose: Sheep antibody to Synaptophysin

Specificity: Specific for Synaptophysin.

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from aa region of 200-300 of mouse Synaptophysin (SYP) conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: Synaptophysin

Background: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. FUNCTION: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. SUBUNIT: Homohexamer or homotetramer. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane, Multi-pass membrane protein.

UniProt: P07825

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity