SENP2 antibody (C-Term)

Catalog No. ABIN356753

The Rabbit Polyclonal anti-SENP2 antibody is suitable to detect SENP2 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for SENP2 antibody (C-Term) (ABIN356753)

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-SENP2 Antibody

Binding Specificity: C-Term

Specificity: This antibody is specific to SENP2 (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SENP2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SENP2

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Alternative Name: SENP2

Background: SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.Synonyms: Axam2, KIAA1331, SMT3-specific isopeptidase 2, Sentrin-specific protease 2, Sentrin/SUMO-specific protease SENP2, Smt3ip2

Gene ID: 59343, 9606

UniProt: Q9HC62

Pathways: Chromatin Binding