SENP8 antibody (N-Term)

Catalog No. ABIN356780

The Rabbit Polyclonal anti-SENP8 antibody is suitable to detect SENP8 in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for SENP8 antibody (N-Term) (ABIN356780)

Target: SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SENP8 Antibody

Binding Specificity: N-Term

Specificity: This antibody is specific to SENP8 (N-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SENP8.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SENP8

Target: SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))

Alternative Name: SENP8

Background: NEDD8 is a ubiquitin-like protein that becomes conjugated to the cullin subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. SENP8 is a protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.Synonyms: DEN1, Deneddylase-1, NEDD8-specific protease 1, NEDP1, PRSC2, Protease cysteine 2, Sentrin-specific protease 8, Sentrin/SUMO-specific protease SENP8

Gene ID: 123228, 9606

UniProt: Q96LD8