TXNL1 antibody (C-Term)

Catalog No. ABIN356852

The Rabbit Polyclonal anti-TXNL1 antibody is suitable to detect TXNL1 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for TXNL1 antibody (C-Term) (ABIN356852)

Target: TXNL1 (Thioredoxin-Like 1 (TXNL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TXNL1 Antibody

Binding Specificity: C-Term

Specificity: This antibody is specific to TXNL1 (TRP32/TrxL) (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human TrxL.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for TXNL1

Target: TXNL1 (Thioredoxin-Like 1 (TXNL1))

Alternative Name: TXNL1

Background: Thioredoxins are a group of small redox active proteins possessing a conserved active site sequence. TrxL (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43 % identical to human TXN, and a C terminal domain, which shows no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein, compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TrxL does not serve as a substrate for thioredoxin reductase in an insulin assay.Synonyms: 32 kDa thioredoxin-related protein, TRP32, TXL, TXNL, Thioredoxin-like protein 1

Gene ID: 9352, 9606

UniProt: O43396

Pathways: Cell RedoxHomeostasis