TXNL1 antibody (C-Term, Trp32)

Catalog No. ABIN388135

This Rabbit Polyclonal antibody specifically detects TXNL1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TXNL1 antibody (C-Term, Trp32) (ABIN388135)

Target: TXNL1 (Thioredoxin-Like 1 (TXNL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB5394

Product Details anti-TXNL1 Antibody

Binding Specificity: AA 256-289, C-Term, Trp32

Predicted Reactivity: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TXNL1 (TRP32/TrxL) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-289 amino acids from the C-terminal region of human TXNL1 (TRP32/TrxL).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TXNL1

Target: TXNL1 (Thioredoxin-Like 1 (TXNL1))

Alternative Name: TXNL1 (/TrxL)

Background: Thioredoxins are a group of small redox active proteins possessing a conserved active site sequence. TrxL (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43 % identical to human TXN, and a C terminal domain, which shows no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein, compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TrxL does not serve as a substrate for thioredoxin reductase in an insulin assay.

Gene ID: 9352

NCBI Accession: NP_004777

UniProt: O43396

Pathways: Cell RedoxHomeostasis