PDE8A antibody (Middle Region)

Catalog No. ABIN356970

The Rabbit Polyclonal anti-PDE8A antibody (ABIN356970) specifically detects PDE8A in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for PDE8A antibody (Middle Region) (ABIN356970)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PDE8A Antibody

Binding Specificity: Middle Region

Specificity: This antibody detects PDE8A at Center.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human PDE8A.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

Background: PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.Synonyms: 5'-cyclic phosphodiesterase 8A, FLJ16150, High affinity cAMP-specific and IBMX-insensitive 3', HsT19550, Phosphodiesterase 8A, cAMP-specific cyclic nucleotide phosphodiesterase 8A

Molecular Weight: 93173 Da

Gene ID: 5151, 9606

UniProt: O60658

Pathways: cAMP Metabolic Process