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ALDH6A1 antibody (N-Term)

The Rabbit Polyclonal anti-ALDH6A1 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect ALDH6A1 in samples from Human.
Catalog No. ABIN356978

Quick Overview for ALDH6A1 antibody (N-Term) (ABIN356978)

Target

See all ALDH6A1 Antibodies
ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Reactivity

  • 59
  • 10
  • 8
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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Human

Host

  • 45
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Rabbit

Clonality

  • 50
  • 9
Polyclonal

Conjugate

  • 33
  • 5
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  • 3
  • 3
  • 1
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  • 1
This ALDH6A1 antibody is un-conjugated

Application

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  • 8
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  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    • 1
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    N-Term

    Specificity

    This antibody detects ALDH6A1 at N-term.

    Purification

    Protein A column, followed by peptide affinity purification. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    Immunogen

    KLH conjugated synthetic peptide selected from the N-terminal region of human ALDH6A1

    Isotype

    Ig Fraction
  • Application Notes

    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target

    ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

    Alternative Name

    ALDH6A1 / MMSDH

    Background

    ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.Synonyms: Aldehyde dehydrogenase family 6 member A1, Malonate-semialdehyde dehydrogenase [acylating], Methylmalonate-semialdehyde dehydrogenase [acylating] mitochondrial

    Molecular Weight

    57858 Da

    Gene ID

    4329, 9606

    UniProt

    Q02252

    Pathways

    Brown Fat Cell Differentiation
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